s99591

• Gene Symbol: Arrb1
• Gene Name: arrestin, beta 1
• Gene Aliases: 1200006I17Rik, AW208571, G430100A01Rik
• Chromosome Location: Chr.7: 99535486 - 99606772 on Build GRCm38
• UniGene ID: Mm.260193
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Arrb1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_177231.2	NP_796205.1	5	514
	NM_178220.3	NP_835738.1	5	514
GenBank mRNA	AK052588.1	-	5	291
	AK090090.1	-	5	341
	AK144054.1	-	5	313
	AK147508.1	-	5	515
	AK147566.1	-	5	535
	AK165514.1	-	5	313
	BC108969.1	-	5	281	40047224
	BC108970.1	-	5	281	40047225

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

activation of MAPK activity
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
G-protein coupled receptor internalization
positive regulation of receptor internalization
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
transport
endocytosis
receptor-mediated endocytosis
signal transduction
G-protein coupled receptor signaling pathway
phototransduction
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of signal transduction
protein transport
protein ubiquitination
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
positive regulation of protein binding
negative regulation of interleukin-6 production
negative regulation of interleukin-8 production
positive regulation of peptidyl-serine phosphorylation
negative regulation of GTPase activity
positive regulation of smooth muscle cell apoptotic process
positive regulation of Rho protein signal transduction
positive regulation of histone acetylation
positive regulation of insulin secretion involved in cellular response to glucose stimulus
follicle-stimulating hormone signaling pathway
stress fiber assembly
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of histone H4 acetylation

Function(s)

GTPase activator activity
insulin-like growth factor receptor binding
protein binding
transcription factor binding
estrogen receptor binding
mitogen-activated protein kinase kinase binding
ubiquitin protein ligase binding
alpha-1A adrenergic receptor binding
alpha-1B adrenergic receptor binding
angiotensin receptor binding
follicle-stimulating hormone receptor binding
V2 vasopressin receptor binding
AP-2 adaptor complex binding
clathrin adaptor activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
transcription regulatory region DNA binding
ion channel binding
protein phosphorylated amino acid binding
phosphoprotein binding