1-(2-Methoxyphenyl)piperazine, 98%, Thermo Scientific™

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
It is used as pharmaceutical intermediate. N-alkylated 1-(2-methyoxyphenyl)piperazines markedly improved affinity and selectivity of the dopamine D3 receptor which is recognized as a potential therapeutic target for the treatment of various neurological and psychiatric disorders.

Solubility
Soluble in chloroform, ethyl acetate, and methanol. Insoluble in water

Notes
Air sensitive. Store at room temperature. Keep away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 35386-24-4
• Molecular Formula: C11H18Cl2N2O
• Molecular Weight (g/mol): 265.18
• MDL Number: MFCD00005958
• InChI Key: ZGWQDMTYAQEMHA-UHFFFAOYSA-N
• Synonym: 1-2-methoxyphenyl piperazine, 1-2-methoxy-phenyl-piperazine, 1-o-methoxyphenyl piperazine, 2-mpp, 1-2-methoxyphenyl-piperazine, n-2-methoxyphenyl piperazine, unii-81njo1330a, 1-2-methoxy phenyl piperazine, 2-methoxyphenylpiperazine, piperazine, 1-2-methoxyphenyl
• PubChem CID: 1346
• SMILES: [H+].[H+].[Cl-].[Cl-].COC1=CC=CC=C1N1CCNCC1

• Melting Point: 35°C to 39°C
• Density: 1.106
• Boiling Point: 130°C to 133°C (0.1 mmHg)
• Flash Point: >110°C (230°F)
• Quantity: 5 g
• UN Number: UN2923
• Beilstein: 167888
• Sensitivity: Air Sensitive
• Solubility Information: Soluble in chloroform,ethyl acetate,and methanol. Insoluble in water
• IUPAC Name: 1-(2-methoxyphenyl)piperazine
• Formula Weight: 192.26
• Percent Purity: 98%
• Chemical Name or Material: 1-(2-Methoxyphenyl)piperazine

Safety and Handling

Hazard Category	H302+H312-H314
Hazard Statement	GHS H Statement H301-H314-H318 Toxic if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE SOLIDS, TOXIC, N.O.S.
EINECSNumber	252-537-7
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only