1-Amino-3,6,9,12-tetraoxapentadec-14-yne

Description

Acetylene containing reagent with PEG spacer and carboxyl reactivity | CAS: 1013921-36-2 | C11H21NO4 | 231.292 g/mol

1-Amino-3,6,9,12-tetraoxapentadec-14-yne is used as a acetylene containing reagent with PEG spacer and carboxyl reactivity. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification of carboxylic acid containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Amino-3,6,9,12-tetraoxapentadec-14-yne is used as a acetylene containing reagent with PEG spacer and carboxyl reactivity. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification of carboxylic acid containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character.

Solubility
Soluble in DMSO, DMF, DCM, THF, or chloroform.

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers..

Specifications

Chemical Identifiers

• CAS: 1013921-36-2
• Molecular Formula: C11H21NO4
• Molecular Weight (g/mol): 231.292
• MDL Number: MFCD22380736
• InChI Key: QDLPAHLHHBCWOW-UHFFFAOYSA-N
• Synonym: 3,6,9,12-tetraoxapentadec-14-yn-1-amine, amino-peg4-alkyne, propyne-peg4-amine, h2n-peg4-propyne, propyne-peg4-nh2, propargyl-peg4-amine, 1-amino-3,6,9,12-tetraoxapentadec-14-yne, hc inverted exclamation markoc-ch2-peg4-nh2, 2-2-2-2-propargyloxy ethoxy ethoxy ethoxy ethylamine
• PubChem CID: 86580391
• IUPAC Name: 2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethanamine
• SMILES: C#CCOCCOCCOCCOCCN

• Color: Yellow
• Linear Formula: NH₂CH₂CH₂(OCH₂CH₂)₃OCH₂C≡CH
• Quantity: 500 mg
• Solubility Information: Soluble in DMSO,DMF,DCM,THF,or chloroform.
• Formula Weight: 231.29
• Physical Form: Solid
• Chemical Name or Material: 1-Amino-3,6,9,12-tetraoxapentadec-14-yne

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only