1-Bromo-3-chlorobenzene, 99%

Description

CAS: 108-37-2 | C6H4BrCl | 191.45 g/mol

1-Bromo-3-chlorobenzene undergoes bromine-magnesium exchange reactions with i-PrMgCl-LiCl in THF at 0°C and is strongly accelerated by electron-withdrawing substituents. It acts as test substrate to study the application of a new catalytic system for cyanation of various aryl halides using K4[Fe(CN)6] as cyanating source.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Bromo-3-chlorobenzene undergoes bromine-magnesium exchange reactions with i-PrMgCl-LiCl in THF at 0°C and is strongly accelerated by electron-withdrawing substituents. It acts as test substrate to study the application of a new catalytic system for cyanation of various aryl halides using K4[Fe(CN)6] as cyanating source.

Solubility
Not miscible in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 108-37-2
• Molecular Formula: C6H4BrCl
• Molecular Weight (g/mol): 191.45
• MDL Number: MFCD00000568
• InChI Key: JRGGUPZKKTVKOV-UHFFFAOYSA-N
• Synonym: 3-bromochlorobenzene, m-bromochlorobenzene, 3-chlorobromobenzene, benzene, 1-bromo-3-chloro, m-chlorobromobenzene, 1-chloro-3-bromobenzene, 3-chlorophenyl bromide, m-chlorophenyl bromide, m-bromophenyl chloride, 3-bromo-1-chlorobenzene
• PubChem CID: 7928
• IUPAC Name: 1-bromo-3-chlorobenzene
• SMILES: ClC1=CC=CC(Br)=C1

• Melting Point: -22°C
• Density: 1.63
• Boiling Point: 195°C to 196°C
• Quantity: 500 g
• Odor: Aromatic
• Refractive Index: 1.577
• Beilstein: 1446353
• Solubility Information: Not miscible in water.
• Formula Weight: 191.46
• Percent Purity: 99%
• Chemical Name or Material: 1-Bromo-3-chlorobenzene

Safety and Handling

Hazard Category	H227-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335-H227 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.
Precautionary Statement	P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c
EINECSNumber	203-575-8
RTECSNumber	CY9005000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only