1-Chloroethyl chloroformate, 98%

Description

CAS: 50893-53-3 | C3H4Cl2O2 | 142.96 g/mol

1-Chloroethyl chloroformate acts as a reagent in the selective N-dealkylation of tertiary amines. It is also used as a reactant in the preparation of alkyl 1-chloroethyl carbonates. Further, it is used for N-demethylation reaction in the determination of multiple drugs of abuse in biological fluids using capillary electrophoresis with native fluorescence and laser-induced fluorescence detection. It plays an important role as a catalyst for the chemoselective desilylation of silyl-protected alcohols. In addition to this, it is used to cleave benzhydryl groups from amines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Chloroethyl chloroformate acts as a reagent in the selective N-dealkylation of tertiary amines. It is also used as a reactant in the preparation of alkyl 1-chloroethyl carbonates. Further, it is used for N-demethylation reaction in the determination of multiple drugs of abuse in biological fluids using capillary electrophoresis with native fluorescence and laser-induced fluorescence detection. It plays an important role as a catalyst for the chemoselective desilylation of silyl-protected alcohols. In addition to this, it is used to cleave benzhydryl groups from amines.

Solubility
Miscible with most organic solvents.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agent, strong base, alcohols and amines.

Specifications

Chemical Identifiers

• CAS: 50893-53-3
• Molecular Formula: C3H4Cl2O2
• Molecular Weight (g/mol): 142.96
• MDL Number: MFCD00000647
• InChI Key: QOPVNWQGBQYBBP-UHFFFAOYNA-N
• Synonym: 1-chloroethyl chloroformate, chloroformic acid 1-chloroethyl ester, 1-chloro ethyl chloroformate, 1-chloroethylchloroformate, carbonochloridic acid, 1-chloroethyl ester, ace-cl, alpha-chloroethyl chloroformate, chloro 1-chloroethoxy methanone, .alpha.-chloroethyl chloroformate, pubchem17418
• PubChem CID: 521305
• IUPAC Name: 1-chloroethyl carbonochloridate
• SMILES: CC(Cl)OC(Cl)=O

• Melting Point: -65°C
• Density: 1.312
• Boiling Point: 119°C to 121°C
• Flash Point: 45°C (113°F)
• Refractive Index: 1.423
• Quantity: 5 g
• UN Number: UN2742
• Beilstein: 1747601
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with most organic solvents.
• Formula Weight: 142.97
• Percent Purity: 98%
• Chemical Name or Material: 1-Chloroethyl chloroformate

Safety and Handling

Hazard Category	H226-H302-H314-H330
Hazard Statement	GHS H Statement H330-H314-H318-H226-H302 Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapor. Harmful if swallowed.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: CHLOROFORMATES, TOXIC, CORROSIVE, FLAMMABLE, N.O.S.
EINECSNumber	256-834-2
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only