1-Methyl-1H-pyrazole-4-boronic acid pinacol ester, 97%, Thermo Scientific Chemicals

Catalog No.	Quantity
AAH5313903	1 g

Catalog No. AAH5313903 Supplier Thermo Scientific Chemicals Supplier No. H5313903

Description

It is a reagent used for Suzuki-Miyaura cross-coupling reactions, transesterification reactions. It is involved in several reactions as a reagent for the preparation of aminothiazoles as γ-secretase modulators,amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy, pyridine derivatives as TGF-β1 and active A signaling inhibitors and MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a reagent used for Suzuki-Miyaura cross-coupling reactions, transesterification reactions. It is involved in several reactions as a reagent for the preparation of aminothiazoles as γ-secretase modulators,amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy, pyridine derivatives as TGF-β1 and active A signaling inhibitors and MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer.

Solubility
Slightly soluble in water.

Notes
Store in cool dry place. Ensure proper ventilation. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 761446-44-0
• Molecular Formula: C10H17BN2O2
• Molecular Weight (g/mol): 208.07
• MDL Number: MFCD03789259
• InChI Key: UCNGGGYMLHAMJG-UHFFFAOYSA-N
• Synonym: 1-methyl-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-1h-pyrazole, 1-methylpyrazole-4-boronic acid pinacol ester, 1-methyl-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl pyrazole, 1-methyl-1h-pyrazole-4-boronic acid pinacol ester, 1-methyl-4-tetramethyl-1,3,2-dioxaborolan-2-yl-1h-pyrazole, 1-methyl-pyrazole-4-boronic acid pinacol ester, 1-methyl-4-4,4,5,5-tetramethyl-1,3,2 dioxaborolan-2-yl-1h-pyrazole, 1h-pyrazole, 1-methyl-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl, 1-methyl-4-tetramethyl-1,3,2-dioxaborolan-2-yl pyrazole, 1-methyl-4-pyrazoleboronic acid pinacol ester
• PubChem CID: 2773987
• IUPAC Name: 1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
• SMILES: CN1C=C(C=N1)B1OC(C)(C)C(C)(C)O1

• Melting Point: 59°C to 64°C
• Quantity: 1 g
• Solubility Information: Slightly soluble in water.
• Formula Weight: 208.07
• Percent Purity: 97%
• Chemical Name or Material: 1-Methyl-1H-pyrazole-4-boronic acid pinacol ester

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H301-H315-H319-H335 Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only