13-cis-Retinoic acid

Description

CAS: 4759-48-2 | C20H28O2 | 300.442 g/mol

13-cis-Retinoic acid is used to inhibits cell proliferation and induces cell differentiation. 13-cis-Retinoic acid is primarily used in the treatment of severe recalcitrant nodular acne.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in chloroform, dimethyl sulfoxide, water, ethanol, and ether.

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 4759-48-2
• Molecular Formula: C20H28O2
• Molecular Weight (g/mol): 300.442
• MDL Number: MFCD00079542
• InChI Key: SHGAZHPCJJPHSC-RVDNBNLISA-N
• Synonym: Isotretinoin
• PubChem CID: 131954766
• IUPAC Name: (2Z,4E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
• SMILES: CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C

• Melting Point: 172°C to 175°C
• Color: Yellow to Orange
• Quantity: 500 mg
• Merck Index: 14,5228
• Solubility Information: Soluble in chloroform,dimethyl sulfoxide,water,ethanol,and ether.
• Formula Weight: 300.44
• Physical Form: Powder
• Chemical Name or Material: 13-cis-Retinoic acid

Safety and Handling

Hazard Category	H315-H319-H335-H360
Hazard Statement	GHS H Statement H360-H315-H319-H335 May damage fertility or the unborn child. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c
EINECSNumber	225-296-0
RTECSNumber	VH6440000
TSCA	Yes
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only