Invitrogen™ 14-3-3 theta Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529421

Catalog No. PIPA529421

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, Mouse brain. Predicted reactivity: Mouse (99%), Rat (99%), Rabbit (99%), Chicken (98%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

Specifications

• Antigen: 14-3-3 theta
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: YWHAQ
• Gene Alias: 14-3-3; 14-3-3 protein tau; 14-3-3 protein T-cell; 14-3-3 protein theta; 14-3-3 tau; 14-3-3 theta; 14-3-3t; 1C5; 2700028P07Rik; AA409740; AU021156; HS1; OTTHUMP00000165887; Protein HS1; protein tau; protein, theta; R74690; tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Unknown (protein for MGC:127486); YWHAQ
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10971, 22630
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.98 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P27348, P68254
• Gene Symbols: YWHAQ
• Immunogen: Recombinant protein encompassing a sequence within the center region of human 14-3-3 theta. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG