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Cayman Chemical 1400W (hydrochloride), 214358-33-5, 10 mg
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Supplier:  Cayman Chemical 8152010

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Molecular Formula C10H15N3 • 2HCl, Purity ≥98%, Formula Weight 250.2, Synonyms: N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide, dihydrochloride; 1400W is a potent, selective inhibitor of iNOS.{4277} Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 M, and 50 M, respectively.{4277} In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS.{4277} In mice bearing a murine mammary carcinoma, continuous infusion of 1400W at a rate of 10 mg/kg for 6 days decreased tumor weight approximately 50% compared to controls.{5066}.

Catalog No. NC0190933


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