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Tocris Bioscience™ 17-AAG
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Catalog No. 15151 Shop All Novus Biologicals Products
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15-151 1 mg
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Catalog No. 15-151 Supplier Tocris Bioscience™ Supplier No. 1515/1
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Description

Selective Hsp90 inhibitor

Inhibitor of heat shock protein 90 (Hsp90) chaperone activity, and an analog of geldanamycin (Cat. No. 1368). Subsequently inhibits the activity of oncogenic proteins such as p185erbB-2 (IC50 = 31 nM), N-ras, Ki-ras and c-Akt. Antitumor in vivo. Also protects neuroprogenitor cells against stress-induced apoptosis at low concentrations (10 nM) in vitro.

Chemical Identifiers

CAS 75747-14-7
Molecular Formula C31H43N3O8

Specifications

Quantity 1 mg
Formula Weight 585.7
Purity >98%
Molecular Weight (g/mol) 585.698
Chemical Name or Material 17-AAG

Safety and Handling

Recommended Storage Desiccate at -20°C
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