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Tocris Bioscience™ 17-AAG

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Quantity:
1 mg
Description
Inhibitor of heat shock protein 90 (Hsp90) chaperone activity, and an analog of geldanamycin (Cat. No. 1368). Subsequently inhibits the activity of oncogenic proteins such as p185erbB-2 (IC50 = 31 nM), N-ras, Ki-ras and c-Akt. Antitumor in vivo. Also protects neuroprogenitor cells against stress-induced apoptosis at low concentrations (10 nM) in vitro.
Specifications
Specifications
Quantity | 1 mg |
Formula Weight | 585.7 |
Purity | >98% |
Molecular Weight (g/mol) | 585.698 |
Chemical Name or Material | 17-AAG |
Safety and Handling
Recommended Storage | Desiccate at -20°C |
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