2,2-Bis(hydroxymethyl)propionic acid, 98+%

Catalog No.	Quantity
AAL1401436	500 g
AAL1401422	100 g

Catalog No. AAL1401436 Supplier Thermo Scientific Chemicals Supplier No. L1401436

Description

CAS: 4767-03-7 | C5H10O4 | 134.13 g/mol

2,2-Bis(hydroxymethyl)propionic acid is used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays1.2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy Simple derivatives of this acid have been used to construct dendritic architectures via the click azide-acetylene cycloaddition.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,2-Bis(hydroxymethyl)propionic acid is used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays1.2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy Simple derivatives of this acid have been used to construct dendritic architectures via the “click” azide-acetylene cycloaddition.

Solubility
Soluble in acetone (slightly), methanol, and water. Insoluble in benzene.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. It is hygroscopic in nature.

Specifications

Chemical Identifiers

• CAS: 4767-03-7
• Molecular Formula: C5H10O4
• Molecular Weight (g/mol): 134.13
• MDL Number: MFCD00004199
• InChI Key: PTBDIHRZYDMNKB-UHFFFAOYSA-N
• Synonym: 2,2-bis hydroxymethyl propionic acid, dimethylolpropionic acid, 3-hydroxy-2-hydroxymethyl-2-methylpropanoic acid, 2,2-bis hydroxymethyl propanoic acid, propanoic acid, 3-hydroxy-2-hydroxymethyl-2-methyl, 2,2-dimethylolpropionic acid, dimethylol propionic acid, 2,2-bis hydroxymethyl propanoicacid, unii-4nhi8v17mn, 4nhi8v17mn
• PubChem CID: 78501
• IUPAC Name: 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid
• SMILES: CC(CO)(CO)C(=O)O

• Melting Point: 187°C to 191°C
• Quantity: 500 g
• Beilstein: 1756385
• Sensitivity: Hygroscopic
• Merck Index: 14,3253
• Solubility Information: Soluble in acetone (slightly),methanol,and water. Insoluble in benzene.
• Formula Weight: 134.13
• Percent Purity: ≥98%
• Chemical Name or Material: 2,2-Bis(hydroxymethyl)propionic acid

Safety and Handling

Hazard Category	H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280i-P304+P340-P305+P351+P338-P312-P501c
EINECSNumber	225-306-3
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only