2,6-Dichlorobenzoyl chloride, 98%

Description

CAS: 4659-45-4 | C7H3Cl3O | 209.45 g/mol

2,6-Dichlorobenzoyl chloride acts as an important intermediate in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. It is employed in the substrate activity screening method for the rapid development of novel substrates and their conversion into non-peptidic inhibitors of Cys and Ser proteases. It is also used in the preparation of 1-acyliridoles and (-)-aspicilin. In addition to this, it undergoes esterification of (fluoren-9-ylmethoxy)carbonyl (Fmoc)-amino acids to 4-alkoxybenzyl alcohol polystyrene.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,6-Dichlorobenzoyl chloride acts as an important intermediate in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. It is employed in the substrate activity screening method for the rapid development of novel substrates and their conversion into non-peptidic inhibitors of Cys and Ser proteases. It is also used in the preparation of 1-acyliridoles and (-)-aspicilin. In addition to this, it undergoes esterification of (fluoren-9-ylmethoxy)carbonyl (Fmoc)-amino acids to 4-alkoxybenzyl alcohol polystyrene.

Solubility
Miscible with alcohol, ether and acetone. Slightly miscible with heptane. Immiscible with water.

Notes
Moisture sensitive. Incompatible with alcohols, oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 4659-45-4
• Molecular Formula: C7H3Cl3O
• Molecular Weight (g/mol): 209.45
• MDL Number: MFCD00000662
• InChI Key: JBLIDPPHFGWTKU-UHFFFAOYSA-N
• Synonym: benzoyl chloride, 2,6-dichloro, 2,6-dichlorobenzoylchloride, unii-394f6s81wy, 2,6-dichloro-benzoyl chloride, ccris 8617, pubchem18674, acmc-209k7i, 2.6-dichlorobenzoylchloride, dsstox_cid_12891, dsstox_rid_79043
• PubChem CID: 78392
• IUPAC Name: 2,6-dichlorobenzoyl chloride
• SMILES: C1=CC(=C(C(=C1)Cl)C(=O)Cl)Cl

• Melting Point: 15°C to 18°C
• Density: 1.463
• Boiling Point: 130°C to 132°C (15 mmHg)
• Flash Point: >110°C (230°F)
• Refractive Index: 1.56
• Quantity: 50 g
• UN Number: UN3265
• Beilstein: 639531
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with alcohol,ether and acetone. Slightly miscible with heptane. Immiscible with water.
• Formula Weight: 209.46
• Percent Purity: 98%
• Chemical Name or Material: 2,6-Dichlorobenzoyl chloride

Safety and Handling

Hazard Category	H314
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	225-102-4
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only