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2-Butynoic acid, 98%
Description
2-Butynoic acid is used as an intermediate in organic synthesis and pharmaceuticals. It is used as a synthon in various reactions, which includes cylcoalkylation of phenols to flavones and chromones. It is involved in the cyclization of gamma-butyrolactones. It is also used in the synthesis of Z-trisubstituted olefins through μ-alkylation. It plays an important role in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs, which finds application as anti-cancer agents.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
2-Butynoic acid is used as an intermediate in organic synthesis and pharmaceuticals. It is used as a synthon in various reactions, which includes cylcoalkylation of phenols to flavones and chromones. It is involved in the cyclization of gamma-butyrolactones. It is also used in the synthesis of Z-trisubstituted olefins through µ-alkylation. It plays an important role in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs, which finds application as anti-cancer agents.
Solubility
Soluble in water. Slightly soluble in methanol and chloroform.
Notes
Store in a cool place. Incompatible with strong oxidizing agents, strong bases and strong reducing agents.
Specifications
Specifications
| Melting Point | 75°C to 79°C |
| Density | 0.964 |
| Boiling Point | 200°C to 203°C |
| Linear Formula | CH3C≡CCO2H |
| Quantity | 5 g |
| UN Number | UN3261 |
| Beilstein | 1740205 |
| Solubility Information | Soluble in water. Slightly soluble in methanol and chloroform. |
| Formula Weight | 84.07 |
| Percent Purity | 98% |
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Safety and Handling
| Hazard Category | H302-H312-H314-H332-H335 |
| Hazard Statement | GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage. |
| Precautionary Statement | P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c |
| DOTInformation | Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. |
| EINECSNumber | 209-695-7 |
| TSCA | Yes |
| Recommended Storage | Keep cold |
RUO – Research Use Only
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