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Cayman Chemical 2AmIno2 ptolylacetIc AcI 5g
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Supplier:  Cayman Chemical 422945 G

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An mPGES-1 inhibitor inhibits PGE2 production in both SK-N-AS human and BV-2 mouse cells (IC50s 0.1 and 2 UM respectively) reduces LPS-induced increases in a variety of cytokines including CCL2 IL-6 and TNF-a in the mouse hippocampus but not kidney without affecting the mRNA expression of Cox2 at 10 mg/kg i.p.

Catalog No. 50-294-3551


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