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3,4-Diaminopyridine, 97%

Catalog No. AAA1246503
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Quantity:
1 g
5 g
25 g

CAS: 54-96-6 | C5H7N3 | 109.132 g/mol

It is a potassium channel blocker in nerve terminals. It inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a potassium channel blocker in nerve terminals. It inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract.

Solubility
Soluble in water (24 mg/ml at 20°C), alcohol. Slightly soluble in ether.

Notes
Store under cool dry place. Ensure good ventilation. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 54-96-6
Molecular Formula C5H7N3
Molecular Weight (g/mol) 109.132
MDL Number MFCD00006401
InChI Key OYTKINVCDFNREN-UHFFFAOYSA-N
Synonym 3,4-diaminopyridine, amifampridine, 3,4-pyridinediamine, firdapse, diamino-3,4 pyridine, 4,5-diaminopyridine, 3,4-dap, amifampridin, zenas, pyridine, 3,4-diamino
PubChem CID 5918
IUPAC Name pyridine-3,4-diamine
SMILES C1=CN=CC(=C1N)N

Specifications

Melting Point 217°C to 220°C
Flash Point 240°C (464°F)
Odor Unpleasant
Quantity 1 g
UN Number UN2811
Beilstein 110232
Merck Index 14,2986
Solubility Information Soluble in water (24mg/ml at 20°C),alcohol. Slightly soluble in ether.
Formula Weight 109.13
Percent Purity ≥98%
Chemical Name or Material 3,4-Diaminopyridine
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Hazard Category H300+H330-H311-H315-H318-H335
Hazard Statement GHS H Statement
H300-H330-H312-H319
Fatal if swallowed.
Fatal if inhaled.
Harmful in contact with skin.
Causes serious eye irritation.
Precautionary Statement P260-P264b-P270-P271-P280-P284-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P361-P363-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber 200-220-9
RTECSNumber US7600000
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only

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