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3,4-Dimethoxy-3-cyclobutene-1,2-dione, 98%
Description
3,4-Dimethoxy-3-cyclobutene-1,2-dione (Dimethyl squarate) finds it uses in the synthesis of chiral squaramides, highly enantioselective catalyst for the Friedel-Crafts reactions of indoles, 3-(hydroxyamino)-4-methoxy-3-cyclobutene-1,2-dione, squarate derivatives of the O-SP-core antigens, methyl squarate derivative of the Ogawa O-SP-core antigen, o-quinodimethanes, benzocyclobutenes, quinones. It is employed as a starting material in the preparation of o-quinodimethanes, benzocyclobutenes, and quinones.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
3,4-Dimethoxy-3-cyclobutene-1,2-dione (Dimethyl squarate) finds it uses in the synthesis of chiral squaramides, highly enantioselective catalyst for the Friedel-Crafts reactions of indoles, 3-(hydroxyamino)-4-methoxy-3-cyclobutene-1,2-dione, squarate derivatives of the O-SP-core antigens, methyl squarate derivative of the Ogawa O-SP-core antigen, o-quinodimethanes, benzocyclobutenes, quinones. It is employed as a starting material in the preparation of o-quinodimethanes, benzocyclobutenes, and quinones.
Solubility
Very soluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications
Specifications
Melting Point | 53°C to 56°C |
Quantity | 5 g |
Synonym | 3,4-dimethoxy-3-cyclobutene-1,2-dione, dimethyl squarate, squaric acid dimethyl ester, 3-cyclobutene-1,2-dione, 3,4-dimethoxy, 3,4-dimethoxy-cyclobut-3-ene-1,2-dione, dimethoxycyclobut-3-ene-1,2-dione, 3-cyclobutene-1,2-dione,3,4-dimethoxy, 3,4-dimethoxycyclobut-3-en-1,2-dion, dimethoxycyclobutenedione, pubchem13709 |
Solubility Information | Very soluble in water. |
Formula Weight | 142.1 |
Percent Purity | 98% |
Chemical Name or Material | 3,4-Dimethoxy-3-cyclobutene-1,2-dione |
Safety and Handling
Hazard Category | H315-H317-H319-H334-H335 |
Hazard Statement | GHS H Statement H334-H335-H315-H319-H317 May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. |
Precautionary Statement | P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c |
TSCA | No |
Recommended Storage | Keep cold |
RUO – Research Use Only
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