3,5-Bis(trifluoromethyl)aniline, 98%

Catalog No.	Quantity
AAA1528930	250 g
AAA1528909	10 g
AAA1528918	50 g

Catalog No. AAA1528930 Supplier Thermo Scientific Chemicals Supplier No. A1528930

Description

CAS: 328-74-5 | C8H5F6N | 229.125 g/mol

3,5-Bis(trifluoromethyl)aniline was used in the synthesis of N-[2-hydroxy-1-naphthylidene]-3, 5-bis(trifluoromethyl)aniline, Schiff?s base and 5,7-bis(trifluoromethyl)aniline. It was also used in the synthesis of N-1-phenylethyl-3,5-bis(trifluoromethyl)aniline via titanium-catalyzed hydroamination reaction and N,N?-bis[3,5-bis(tri-fluoromethyl)phenyl]thiourea, organocatalyst.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3,5-Bis(trifluoromethyl)aniline was used in the synthesis of N-[2-hydroxy-1-naphthylidene]-3, 5-bis(trifluoromethyl)aniline, Schiff′s base and 5,7-bis(trifluoromethyl)aniline. It was also used in the synthesis of N-1-phenylethyl-3,5-bis(trifluoromethyl)aniline via titanium-catalyzed hydroamination reaction and N,N′-bis[3,5-bis(tri-fluoromethyl)phenyl]thiourea, organocatalyst.

Solubility
Not miscible in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 328-74-5
• Molecular Formula: C8H5F6N
• Molecular Weight (g/mol): 229.125
• MDL Number: MFCD00000394
• InChI Key: CDIDGWDGQGVCIB-UHFFFAOYSA-N
• Synonym: 3,5-bis trifluoromethyl aniline, 3,5-di trifluoromethyl aniline, benzenamine, 3,5-bis trifluoromethyl, 3,5-bis trifluoromethyl benzenamine, 3',5'-bis-trifluoromethyl aniline, 3,5-bis-trifluoromethylaniline, alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-3,5-xylidine, 3,5-bis-trifluoromethyl-phenylamine, aniline, 3,5-bis trifluoromethyl
• PubChem CID: 9480
• IUPAC Name: 3,5-bis(trifluoromethyl)aniline
• SMILES: C1=C(C=C(C=C1C(F)(F)F)N)C(F)(F)F

• Boiling Point: 75°C to 78°C (10 mmHg)
• Flash Point: 83°C (181°F)
• Odor: Recognizable
• Quantity: 250 g
• UN Number: UN2810
• Beilstein: 654318
• Formula Weight: 229.13
• Percent Purity: 98%
• Chemical Name or Material: 3,5-Bis(trifluoromethyl)aniline

Safety and Handling

Hazard Category	Danger
Hazard Statement	GHS H Statement H331-H373-H227-H302-H312-H315-H319 Toxic if inhaled. May cause damage to organs through prolonged or repeated exposure. Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	GHS P Statement P210-P260-P261-P305+P351+P338-P405-P501a Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapors/spray. Avoid breathing dust/fume/gas/mist/vapors/spray. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC, LIQUIDS, ORGANIC, N.O.S.
RTECSNumber	ZE9800000
TSCA	TSCA

SDS

RUO – Research Use Only