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4',7-Dihydroxyisoflavone, 97%, Thermo Scientific Chemicals
Description
4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
4′,7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
Solubility
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
Specifications
Specifications
Melting Point | 328°C to 332°C (decomposition) |
Quantity | 25 g |
Beilstein | 231523 |
Merck Index | 14,2801 |
Solubility Information | Insoluble in water. Soluble in DMSO (25mg/ml),ethanol (2mg/ml),DMF (10mg/ml),and 1:10 DMSO:PBS (pH 7.2) (0.15mg/ml). |
Formula Weight | 254.24 |
Percent Purity | 97% |
Chemical Name or Material | 4',7-Dihydroxyisoflavone |
Safety and Handling
Hazard Category | H315-H319 |
Hazard Statement | GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
Precautionary Statement | P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362 |
EINECSNumber | 207-635-4 |
RTECSNumber | DJ3100040 |
TSCA | No |
RUO – Research Use Only
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