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  7. 4',7-Dihydroxyisoflavone, 97%, Thermo Scientific Chemicals

4',7-Dihydroxyisoflavone, 97%, Thermo Scientific Chemicals

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Quantity:
1 g
5 g
25 g
486-66-8
C15H10O4
254.241
MFCD00016954
ZQSIJRDFPHDXIC-UHFFFAOYSA-N
daidzein, 4',7-dihydroxyisoflavone, daidzeol, 7,4'-dihydroxyisoflavone, 7-hydroxy-3-4-hydroxyphenyl-4h-chromen-4-one, diadzein, 7-hydroxy-3-4-hydroxyphenyl-4h-1-benzopyran-4-one, 4h-1-benzopyran-4-one, 7-hydroxy-3-4-hydroxyphenyl, 7-hydroxy-3-4-hydroxyphenyl chromen-4-one, 7-hydroxy-3-4-hydroxyphenyl-4-benzopyrone
5281708
CHEBI:28197
7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one
C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O
486-66-8
C15H10O4
254.241
MFCD00016954
ZQSIJRDFPHDXIC-UHFFFAOYSA-N
daidzein, 4',7-dihydroxyisoflavone, daidzeol, 7,4'-dihydroxyisoflavone, 7-hydroxy-3-4-hydroxyphenyl-4h-chromen-4-one, diadzein, 7-hydroxy-3-4-hydroxyphenyl-4h-1-benzopyran-4-one, 4h-1-benzopyran-4-one, 7-hydroxy-3-4-hydroxyphenyl, 7-hydroxy-3-4-hydroxyphenyl chromen-4-one, 7-hydroxy-3-4-hydroxyphenyl-4-benzopyrone
5281708
CHEBI:28197
7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one
C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O

Description

4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′,7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

Solubility
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
Melting Point 328°C to 332°C (decomposition)
Quantity 25 g
Beilstein 231523
Merck Index 14,2801
Solubility Information Insoluble in water. Soluble in DMSO (25mg/ml),ethanol (2mg/ml),DMF (10mg/ml),and 1:10 DMSO:PBS (pH 7.2) (0.15mg/ml).
Formula Weight 254.24
Percent Purity 97%
Chemical Name or Material 4',7-Dihydroxyisoflavone

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362

H315-H319

EINECSNumber : 207-635-4

RTECSNumber : DJ3100040

TSCA : No

SDS

RUO – Research Use Only

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