4-Amino-1-Boc-piperidine, 97%

Description

CAS: 87120-72-7 | C10H21N2O2 | 201.29 g/mol

4-Amino-1-Boc-piperidine is a chemical reagent used in the preparation of pharmaceutical compounds. Used in the synthesis of bromodomain inhibitors as well as HepG2 cell cycle inhibitors used in anti-tumor therapy. Also employed in a microwave-assisted solid-phase synthesis of N-substituted piperidines via direct annulation of primary amines with resin-bound dimesylates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Amino-1-Boc-piperidine is a chemical reagent used in the preparation of pharmaceutical compounds. Used in the synthesis of bromodomain inhibitors as well as HepG2 cell cycle inhibitors used in anti-tumor therapy. Also employed in a microwave-assisted solid-phase synthesis of N-substituted piperidines via direct annulation of primary amines with resin-bound dimesylates.

Solubility
Insoluble in water.

Notes
Air Sensitive, store away from air. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 87120-72-7
• Molecular Formula: C10H21N2O2
• Molecular Weight (g/mol): 201.29
• MDL Number: MFCD01076201
• InChI Key: LZRDHSFPLUWYAX-UHFFFAOYSA-O
• Synonym: 4-amino-1-boc-piperidine, 1-boc-4-aminopiperidine, n-boc-4-aminopiperidine, n-boc-4-amino-piperidine, 4-amino-1-n-boc-piperidine, 4-amino-n-boc piperidine, 1-boc-4-amino piperidine, 1-n-boc-4-aminopiperidine, 1-t-butoxycarbonyl-4-aminopiperidine, n-1-boc-4-aminopiperidine
• PubChem CID: 1268291
• IUPAC Name: tert-butyl 4-aminopiperidine-1-carboxylate
• SMILES: CC(C)(C)OC(=O)N1CCC([NH3+])CC1

• Melting Point: 44°C to 48°C
• Quantity: 1 g
• UN Number: UN3259
• Sensitivity: Air Sensitive
• Solubility Information: Insoluble in water.
• Formula Weight: 200.28
• Percent Purity: 97%
• Chemical Name or Material: 4-Amino-1-Boc-piperidine

Safety and Handling

Hazard Category	H302-H314
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only