4-Bromo-2-methoxypyridine, 98%

Description

CAS: 100367-39-3 | C6H6BrNO | 188.024 g/mol

4-Bromo-2-methoxypyridine used in the synhesis of Imidazo [1, 2-a] pyrimidines. Suzuki coupling between 4-methoxyphenylboronic acid and 4-bromo-2-methoxypyridine affords 1, 5-disubstituted pyridones. Starting material used in a synthesis of crown-ester-bipyridines and viologens via sodium or nickel reductive coupling, side chain oxidation and esterification.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Bromo-2-methoxypyridine used in the synhesis of Imidazo [1, 2-a] pyrimidines. Suzuki coupling between 4-methoxyphenylboronic acid and 4-bromo-2-methoxypyridine affords 1, 5-disubstituted pyridones. Starting material used in a synthesis of crown-ester-bipyridines and viologens via sodium or nickel reductive coupling, side chain oxidation and esterification.

Solubility
Slightly soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Specifications

Chemical Identifiers

• CAS: 100367-39-3
• Molecular Formula: C6H6BrNO
• Molecular Weight (g/mol): 188.024
• MDL Number: MFCD08277268
• InChI Key: YFTGMMXMLPTTAY-UHFFFAOYSA-N
• Synonym: 2-methoxy-4-bromopyridine, 4-bromo-2-methoxy-pyridine, pyridine, 4-bromo-2-methoxy, pubchem6657, ksc494g1d, acmc-1c790, abbypharma ap-17-5965
• PubChem CID: 14062309
• IUPAC Name: 4-bromo-2-methoxypyridine
• SMILES: COC1=NC=CC(=C1)Br

• Melting Point: 25°C to 26°C
• Color: White to Yellow
• Boiling Point: 87°C (15 mmHg)
• Quantity: 5 g
• Beilstein: 115199
• Solubility Information: Slightly soluble in water.
• Formula Weight: 188.02
• Percent Purity: 98%
• Physical Form: Low Melting Solid
• Chemical Name or Material: 4-Bromo-2-methoxypyridine

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
storageNote1	2° to 8°C
Recommended Storage	Keep cold

SDS

RUO – Research Use Only