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4-Bromobenzonitrile, 98+%, Thermo Scientific™

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Quantity:
10g
50g
250g
623-00-7
C7H4BrN
182.02
MFCD00001811
HQSCPPCMBMFJJN-UHFFFAOYSA-N
p-bromobenzonitrile, benzonitrile, 4-bromo, benzonitrile, p-bromo, 1-bromo-4-cyanobenzene, 4-bromo benzonitrile, 4-cyano-bromobenzene, 4-bromo-4'-cyanobenzene, 4-cyanobromobenzene, bromobenzonitrile-4, 4-bromocyanobenzene
12162
4-bromobenzonitrile
BrC1=CC=C(C=C1)C#N
623-00-7
C7H4BrN
182.02
MFCD00001811
HQSCPPCMBMFJJN-UHFFFAOYSA-N
p-bromobenzonitrile, benzonitrile, 4-bromo, benzonitrile, p-bromo, 1-bromo-4-cyanobenzene, 4-bromo benzonitrile, 4-cyano-bromobenzene, 4-bromo-4'-cyanobenzene, 4-cyanobromobenzene, bromobenzonitrile-4, 4-bromocyanobenzene
12162
4-bromobenzonitrile
BrC1=CC=C(C=C1)C#N

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
4-Bromobenzonitrile is used as reagents and solvents. Reaction of 2-propanol, 4-bromobenzonitrile, and NaH in the presence of 1.5 mol % Pd2(dba)3 and 3 mol % (S)-(-)2,2′-bis(di-p-tolylphosphino)- 1,1′-binaphthyl at 50°C afforded 4-isopropoxy- benzonitrile in 80% isolated yield. The synthesis of 4-cyanobiphenyl at room temperature in a flow injection microreactor, using a supported catalyst, without the addition of a base gave a product yield of 67±7% (n=6). This was achieved by injecting 4-bromobenzonitrile. The 3-arylation of 2,5-dimethylthiophene with 4-bromopropiophenone, 4-trifluoromethylbromobenzene or 4-bromobenzonitrile gave 3-5 in only 38-50% yields in Palladium-catalysed direct 3-or 4-arylation of thiophene derivatives using aryl bromides.

Solubility
Very slightly soluble in water(0.2g/L). Soluble in alcohol and ether.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Density 1.562
Melting Point 111°C to 114°C
Boiling Point 235°C to 237°C
Flash Point 130°C (266°F)
UN Number UN3439
Beilstein 2041518
Quantity 50g
Solubility Information Very slightly soluble in water(0.2g/L). Soluble in alcohol and ether.
Formula Weight 182.03
Percent Purity ≥98%
Chemical Name or Material 4-Bromobenzonitrile
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GHS H Statement
H301-H331-H312-H315-H319-H335
Toxic if swallowed.
Toxic if inhaled.
Harmful in contact with skin.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P312-P330-P363-P501c

H302+H312-H319

DOTInformation : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.

EINECSNumber : 210-764-9

RTECSNumber : DI2460000

TSCA : No

Recommended Storage : Ambient temperatures

RUO – Research Use Only