4-(Bromomethyl)benzoic acid, 97%, Thermo Scientific Chemicals

Description

4-(Bromomethyl)benzoic acid acts as an intermediate in the synthesis of eprosartan, which is used as an antihypertensive agent. Further, it is used in the preparation of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), which is a second generation photosensitizer. In addition to this, it is used in the preparation of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-(Bromomethyl)benzoic acid acts as an intermediate in the synthesis of eprosartan, which is used as an antihypertensive agent. Further, it is used in the preparation of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), which is a second generation photosensitizer. In addition to this, it is used in the preparation of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.

Solubility
Soluble in water.

Notes
Incompatible with bases, amines and oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 6232-88-8
• Molecular Formula: C8H7BrO2
• Molecular Weight (g/mol): 215.046
• MDL Number: MFCD00002567
• InChI Key: CQQSQBRPAJSTFB-UHFFFAOYSA-N
• Synonym: 4-bromomethyl benzoic acid, alpha-bromo-p-toluic acid, benzoic acid, 4-bromomethyl, p-bromomethyl benzoic acid, 4-carboxybenzyl bromide, 4-bromomethyl-benzoic acid, a-bromo-p-toluic acid, p-carboxybenzyl bromide, p-bromomethylbenzoic acid
• PubChem CID: 22599
• IUPAC Name: 4-(bromomethyl)benzoic acid
• SMILES: C1=CC(=CC=C1CBr)C(=O)O

• Melting Point: 223°C to 227°C
• Quantity: 100 g
• UN Number: UN3261
• Beilstein: 1862870
• Solubility Information: Soluble in water.
• Formula Weight: 215.05
• Percent Purity: 97%
• Chemical Name or Material: 4-(Bromomethyl)benzoic acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	228-343-3
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only