4-(Trifluoromethyl)benzoic acid, 98+%

Description

CAS: 455-24-3 | C8H5F3O2 | 190.121 g/mol

4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates via N,N?-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates via N,N′-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.

Solubility
Soluble in water.

Notes
Store in cool, dry conditions in a well sealed container. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 455-24-3
• Molecular Formula: C8H5F3O2
• Molecular Weight (g/mol): 190.121
• MDL Number: MFCD00002562
• InChI Key: SWKPKONEIZGROQ-UHFFFAOYSA-N
• Synonym: 4-trifluoromethyl benzoic acid, p-trifluoromethylbenzoic acid, alpha,alpha,alpha-trifluoro-p-toluic acid, benzoic acid, 4-trifluoromethyl, p-carboxybenzotrifluoride, 4-trifluoromethyl-benzoic acid, a,a,a-trifluoro-p-toluic acid, ptf-boa, 4-carboxybenzotrifluoride
• PubChem CID: 9966
• ChEBI: CHEBI:60696
• IUPAC Name: 4-(trifluoromethyl)benzoic acid
• SMILES: C1=CC(=CC=C1C(=O)O)C(F)(F)F

• Melting Point: 220°C to 222°C
• Boiling Point: 247°C (753 mmHg)
• Quantity: 5 g
• Beilstein: 2049241
• Solubility Information: Soluble in water.
• Formula Weight: 190.12
• Percent Purity: ≥98%
• Chemical Name or Material: 4-(Trifluoromethyl)benzoic acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	207-242-8
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only