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5-Azacytidine, Tocris Bioscience™
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Catalog No. 384250
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

DNA methyltransferase inhibitor

DNA methyltransferase inhibitor. Incorporates into DNA forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves the efficiency of reprogramming of stem cells; induces differentiation of mesenchymal stem cells into cardiomyocytes.

Chemical Identifiers

CAS 320-67-2
Molecular Formula C8H12N4O5
Molecular Weight (g/mol) 244.21
InChI Key NMUSYJAQQFHJEW-KVTDHHQDSA-N
Synonym 5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
PubChem CID 9444
ChEBI CHEBI:2038
IUPAC Name 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
SMILES NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Specifications

Quantity 50 mg
Formula Weight 244.2
Percent Purity >98%
Chemical Name or Material 5-Azacytidine

Safety and Handling

Recommended Storage Store at Room Temperature
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