5-Bromo-2'-Deoxyuridine, MP Biomedicals™

Description

Useful for the study of DNA synthesis. 5-Bromo-2'-Deoxyuridine, MP Biomedicals (5-BrdU) is a thymidine analogue that is incorporated into DNA. It is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently it is us

5-BrdU can be used to label DNA, which can be used in conjunction with BrdU Monoclonal Antibody for the immunohistochemical analysis of cell proliferation. Thymidine analog is used as a mutagen in genetic research. It is selectively incorporated into cellular DNA in place of thymidine during S-phase. It is also used to study cell signaling and other processes that induce cell proliferation.

Specifications

Chemical Identifiers

• CAS: 59-14-3
• Molecular Formula: C9H11BrN2O5
• Molecular Weight (g/mol): 307.10
• MDL Number: MFCD00006529
• InChI Key: WOVKYSAHUYNSMH-RRKCRQDMSA-N
• Synonym: 5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine
• PubChem CID: 6035
• ChEBI: CHEBI:472552
• IUPAC Name: 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
• SMILES: OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O

• Melting Point: 183°C to 193°C
• Quantity: 250 mg
• Solubility Information: Soluble in water (10mg/mL or 50–100mg/mL with heat) or sodium hydroxide (50mg/mL).
• Formula Weight: 307.1
• Percent Purity: ≥99%
• Physical Form: Powder

Safety and Handling

Recommended Storage

−20°C

WARNING: Reproductive Harm - www.P65Warnings.ca.gov