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Invitrogen™ 5-Methylcytosine Monoclonal Antibody (33D3)
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Catalog No. PIMA538432 Shop All Thermo Scientific Products
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100 μg
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PIMA538432 100 μg
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Catalog No. PIMA538432 Supplier Invitrogen™ Supplier No. MA538432
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Description

Mouse Monoclonal Antibody

5-Methylcytosine Monoclonal Antibody for ICC/IF, DB, MeDIP

Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
TRUSTED_SUSTAINABILITY

Specifications

Antigen 5-Methylcytosine
Applications Dot Blot, Methylated DNA Immunoprecipitation, Immunocytochemistry
Classification Monoclonal
Clone 33D3
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Alias 5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3
Host Species Mouse
Immunogen 5-Methylcytosine nucleotide.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG1
Target Molecule Chemical
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