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Apexbio Technology LLC Calcifediol monohydrate 63283-36-3 5mg
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Supplier:  Apexbio Technology LLC A32705

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Calcifediol monohydrate (63283-36-3) is a precursor to the active vitamin D hormone that acts via the vitamin D receptor (VDR) It is designed to modulate vitamin D signaling thereby regulating pathways involved in calcium homeostasis and cellular growth Calcifediol monohydrate exerts its biological activity primarily through VDR activation In bovine parathyroid cells calcifediol reduces parathyroid hormone (PTH) secretion and mRNA expression Studies in T-47D breast cancer cells demonstrate that calcifediol s function involves VDR activation linked to endocytic uptake of vitamin D-binding protein (DBP) Based on these pharmacological properties calcifediol monohydrate holds research potential in studies assessing vitamin D s role in diseases such as colorectal breast ovarian renal pancreatic and prostate cancers

Catalog No. 50-000-92879


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