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ACROBiosystems Recombinant Protein;Human Latent TGF-beta 1 / TGFB1 Protein;HEK293;50UG;TG1,Latent TGFB1,TGFB1,TGF B1,TGF-B1,TGF-beta1,TGF beta1,TGFbeta1,CED,DPD1,DPD-1,LAP,TGFB,TGFbeta,TGF-β1,TGFβ1,TGF-beta,TGF beta,Latent TGF-beta 1
Supplier: ACROBiosystems TG1H524X50UG
Recombinant Protein;Human Latent TGF-beta 1 / TGFB1 Protein;50UG;Human TGFB1, His Tag (TG1-H524x) is expressed from human 293 cells (HEK293). It contains AA Leu 30 - Ser 390 (Accession # P01137-1).;This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 42.6 kDa (monomer). The protein migrates as 37-45 kDa (LAP) and 13 kDa (TGFB1) under reducing (R) condition (SDS-PAGE) due to glycosylation and Interchain disulfide bond.;Immobilized Human TGFB1, His Tag (Cat. No. TG1-H524x) at 5 μg/mL (100 μL/well) can bind Biotinylated Human ITGAV&ITGB6, His Tag, Avi Tag (Cat. No. IT6-H82E4) with a linear range of 1-20 ng/mL (QC tested).;Immobilized Human TGFB1, His Tag (Cat. No. TG1-H524x) at 5 μg/mL (100 μL/well) can bind Human LRRC32, Fc Tag (Cat. No. LR2-H5256) with a linear range of 39-625 ng/mL (Routinely tested).;Human Latent TGFB1, His Tag (Cat. No. TG1-H524x) inhibits the IL-4-dependent proliferation of TF-1 cells. The ED50 for this effect is 0.293-0.406
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