53BP2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 265501AP150UL

Catalog No. 50-173-5372

Description

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Specifications

• Antigen: 53BP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TP53BP2
• Gene Alias: 53BP2, ASPP2, BBP, p53 binding protein 2, p53BP2, PPP1R13A, TP53BP2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7159
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q13625
• Gene Symbols: TP53BP2
• Immunogen: 53BP2 Fusion Protein Ag24907
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG