6-Chloropurine riboside, 98%

Catalog No.	Quantity
AAH5963403	1 g
AAH5963406	5 g

Catalog No. AAH5963403 Supplier Thermo Scientific Chemicals Supplier No. H5963403

Description

CAS: 5399-87-1 | C10H11ClN4O4 | 286.67 g/mol

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

Solubility
Soluble in water. (10.6 mg/mL)

Notes
Keep away from heat and humidity. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 5399-87-1
• Molecular Formula: C10H11ClN4O4
• Molecular Weight (g/mol): 286.67
• MDL Number: MFCD00005738
• InChI Key: XHRJGHCQQPETRH-UHFFFAOYNA-N
• Synonym: 6-chloropurine riboside, chloropurine riboside, 2r,3r,4s,5r-2-6-chloro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol, 6-chloropurine ribonucleoside, 6-chloropurine-9-riboside, 6-chloro-9-ribofuranosyl-9h-purine, 9h-purine, 6-chloro-9-ribofuranosyl, 6-chloropurineriboside, 6-chloro-9-beta-d-ribofuranosyl-9h-purine, 6-chloronebularine
• PubChem CID: 93003
• IUPAC Name: (2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• SMILES: OCC1OC(C(O)C1O)N1C=NC2=C(Cl)N=CN=C12

• Melting Point: 158°C to 162°C (decomposition)
• Color: White
• Quantity: 1 g
• Beilstein: 40573
• Solubility Information: Soluble in water. (10.6mg/mL)
• Formula Weight: 286.67
• Percent Purity: 98%
• Physical Form: Powder
• Chemical Name or Material: 6-Chloropurine riboside

Safety and Handling

EINECSNumber	226-438-4
TSCA	No
storageNote1	-30° to -10°C
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only