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Cayman Chemical 7-BromoheptnoIc AcId 5g
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Supplier:  Cayman Chemical 304205 G

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An L-type calcium channel blocker inhibits calcium-induced contraction of rabbit ear artery (pA2 9 4) induces relaxation of calcium-induced contractions in isolated rat colon and bladder and guinea pig trachea (IC50s 6 7 6 and 7 8 nM respectively) induces negative inotropy in isolated guinea pig ventricular strips (IC50 110 nM) reduces mean blood pressure in spontaneously hypertensive rats (ED25 0 35 mg/kg) and in renal hypertensive dogs (ED25 0 22 mg/kg) inhibits copper-induced oxidation of isolated human LDL at 1 and 5 UM reduces the extension of aortic atheromatous lesions and decreases renal injury in ApoE-/- mice in a model of Western diet-induced atherosclerosis

Catalog No. 50-299-2623


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