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Leica Biosystems 7mL p16 (6H12) BOND RTU Primar
Supplier: Leica Biosystems PA0016U

Antigen Backgroundp16 (INK4a) (Cyclin-dependent kinase inhibitor 2A (CDKN2A)) is a tumour suppressor protein associated with cell cycle progression, specifically in the regulation of transition from G1 phase of the cell cycle in to the S phase. Oncogenic mutations in the CDKN2A gene that encodes p16 (resulting in over or under expression of the protein) is associated with a wide range of cancers and cancer precursor lesions.Disclaimerp16 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
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