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Abcam 8-CPT-cAMP, Cell Permeable, >99% Purity, Solid, 100 mg

Catalog No. 502584601
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50-258-4601 100 mg
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Catalog No. 50-258-4601 Supplier Abcam Supplier No. AB120424100MG
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Membrane-permeable, lipophilic cAMP analog that activates Epac and cAMP-dependent protein kinases.

  • Molecular weight: 493.8 Da
  • Purity: >99%
  • Form: Solid
  • Key properties: Membrane permeable, lipophilic cAMP analog
  • Activity: Activator of Epac, cAMP, and cGMP-dependent protein kinases (PKA/PKG)
  • Selectivity: Site B of cAMP-dependent PKA type II
  • Inhibition: Inhibits cyclic GMP-specific phosphodiesterase (PDE Va), PDE III, and PDE IV (IC50 values of 0.9, 24, and 25 μM, respectively)
  • In vivo effects: Increases heart rate; causes fall in arterial blood pressure and vascular resistance

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Buffer 100% 8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate
Form Solid
Content And Storage Store at -20°C.
Shipping Condition Ambient
Target Molecule Epac, PKA, PKG, Phosphodiesterases (PDE Va, PDE III, PDE IV)
Quantity 100 mg
For Use With (Application) Activator of Epac, cAMP and cGMP-dependent protein kinases (PKA/PKG), Inhibitor of cyclic GMP-specific phosphodiesterase (PDE Va), PDE III and PDE IV
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