8-Methoxypsoralen, 98%

Description

CAS: 298-81-7 | C12H8O4 | 216.19 g/mol

8-Methoxypsoralen, is used in Photochemotherapy (methoxsalen with long wave ultraviolet radiation) is indicated for the repigmentation of idiopathic vitiligo. It is also used in Photopheresis (methoxsalen with long wave ultraviolet radiation of white blood cells) is indicated for use with the UVAR* System in the palliative treatment of the skin manifestations of cutaneous T-cell lymphoma.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
8-Methoxypsoralen, is used in Photochemotherapy (methoxsalen with long wave ultraviolet radiation) is indicated for the repigmentation of idiopathic vitiligo. It is also used in Photopheresis (methoxsalen with long wave ultraviolet radiation of white blood cells) is indicated for use with the UVAR* System in the palliative treatment of the skin manifestations of cutaneous T-cell lymphoma.

Solubility
Soluble in acetone, ethanol (slight), acetic acid, and chloroform (50 mg/ml). Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 298-81-7
• Molecular Formula: C12H8O4
• Molecular Weight (g/mol): 216.19
• MDL Number: MFCD00005009
• InChI Key: QXKHYNVANLEOEG-UHFFFAOYSA-N
• Synonym: methoxsalen, 8-methoxypsoralen, xanthotoxin, meladinine, ammoidin, oxsoralen, meloxine, oxypsoralen, xanthotoxine, meladinin
• PubChem CID: 4114
• ChEBI: CHEBI:18358
• IUPAC Name: 9-methoxyfuro[3,2-g]chromen-7-one
• SMILES: COC1=C2OC=CC2=CC2=C1OC(=O)C=C2

• Melting Point: 146°C to 150°C
• Quantity: 1 g
• Beilstein: 196453
• Sensitivity: Light sensitive
• Merck Index: 14,5988
• Solubility Information: Soluble in acetone,ethanol (slight),acetic acid,and chloroform (50mg/ml). Insoluble in water.
• Formula Weight: 216.2
• Percent Purity: 99%
• Chemical Name or Material: 8-Methoxypsoralen

Safety and Handling

Hazard Category	H302-H314-H340-H350
Hazard Statement	GHS H Statement H301-H340-H350-H318 Toxic if swallowed. May cause genetic defects. May cause cancer. Causes serious eye damage.
Precautionary Statement	P201-P202-P260-P264b-P270-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Hazard Class: 8; Packaging Group: II
EINECSNumber	206-066-9
RTECSNumber	LV1400000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only