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9-cis-Retinoic acid

Catalog No. AAJ62219LB0
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Catalog No. AAJ62219LB0 Supplier Thermo Scientific Chemicals Supplier No. J62219LB0
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Description

CAS: 5300-03-8 | C20H28O2 | 300.44 g/mol

9-cis-Retinoic acid is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. 9-cis-Retinoic acid is an inhibitor of Cox-2 and an activator of RAR α, RAR β, RAR γ and RXR.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
9-cis-Retinoic acid is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. 9-cis-Retinoic acid is an inhibitor of Cox-2 and an activator of RAR α, RAR β, RAR γ and RXR.

Solu
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 5300-03-8
Molecular Formula C20H28O2
Molecular Weight (g/mol) 300.44
MDL Number MFCD00270072
InChI Key SHGAZHPCJJPHSC-YCNIQYBTSA-N
Synonym alitretinoin, 9-cis-retinoic acid, panretin, 9-cis-tretinoin, panrexin, panretyn, panretin gel, toctino, 9-cis retinoic acid, 9 z-retinoic acid
PubChem CID 449171
ChEBI CHEBI:50648
IUPAC Name (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C

Specifications

Melting Point 178°C to 180°C
Quantity 5 mg
Sensitivity Light and moisture sensitive
Merck Index 14,249
Solubility Information Soluble in chloroform (50mg/ml),DMSO (∽25mg/ml),ethanol (25mg/ml),and acetone (25mg/ml). Insoluble in water.
Formula Weight 300.44
Physical Form Powder
Chemical Name or Material 9-cis-Retinoic acid

Safety and Handling

Hazard Category H335-H360D
Hazard Statement GHS H Statement
H360-H315-H319-H335
May damage fertility or the unborn child.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P201-P202-P261-P271-P281-P304+P340-P308+P313-P501c
RTECSNumber VH6450000
TSCA No
storageNote1 -30° to -10°C
Recommended Storage Store at -20°C; Store under Nitrogen
SDS

RUO – Research Use Only

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