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Invitrogen™ A2M Monoclonal Antibody (A5-A9)
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Catalog No. PIMA542577
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Quantity:
100 μL
Catalog No. Quantity
PIMA542577 100 μL
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Catalog No. PIMA542577

Supplier: Invitrogen™ MA542577

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Description

Mouse Monoclonal Antibody

Positive Control: LOVO cell lysates, LO2 cell lysates, Hela, HepG2, human liver tissue, human uterus tissue. Subcellular Location: Secreted. Product has been tested in direct ELISA.

Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.
TRUSTED_SUSTAINABILITY

Specifications

Antigen A2M
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone A5-A9
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene A2M
Gene Accession No. P01023
Gene Alias A2M; A2m1; A2maa; A2MAC1; A2MD; A2mp; Alpha 2 M; Alpha-2-M; Alpha-2-M (A2M); alpha-2-macroglobulin; Alpha-2-macroglobulin-P; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; LOC100061656; Mam; S863 7; S863-7
Gene Symbols A2M
Host Species Mouse
Immunogen Recombinant protein within human Alpha-2-macroglobulin aa 950-1200.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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