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ABclonal Technology CDKN1C/p57 Kip2 Rabbit mAb
SDP

Supplier:  ABclonal Technology A68431000UL

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This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

Catalog No. 50-001-34763


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