AANAT Monoclonal Antibody (OTI6E1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA810161

Catalog No. 50-168-3232

Description

Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function. Large changes in the abundance of AANAT are believed to be responsible for the large day/night rhythms in melatonin synthesis in the pineal gland and retina (1,2). Most research shows that AANAT activity is regulated by controlling the steady-state levels of the protein. Recent research, however, suggests that another mechanism may also play a role in controlling melatonin production without altering AANAT protein and activity. This mechanism may explain the sudden physiological increase in circulating melatonin observed at the onset of the dark period in humans.

Specifications

• Antigen: AANAT
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q16613
• Gene Symbols: AANAT
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-72 of human AANAT produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI6E1
• Conjugate: Unconjugated
• Gene: AANAT
• Gene Alias: DSPS, SNAT
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid