AANAT Monoclonal Antibody (OTI6E1), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-3232	100 μL

Catalog No. 50-168-3232 Supplier OriGene Supplier No. TA810161

Description

Mouse Monoclonal Antibody

Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function. Large changes in the abundance of AANAT are believed to be responsible for the large day/night rhythms in melatonin synthesis in the pineal gland and retina (1,2). Most research shows that AANAT activity is regulated by controlling the steady-state levels of the protein. Recent research, however, suggests that another mechanism may also play a role in controlling melatonin production without altering AANAT protein and activity. This mechanism may explain the sudden physiological increase in circulating melatonin observed at the onset of the dark period in humans.

Specifications

• Antigen: AANAT
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI6E1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: AANAT
• Gene Accession No.: Q16613
• Gene Alias: DSPS, SNAT
• Gene Symbols: AANAT
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-72 of human AANAT produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 15
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1