Invitrogen™ ABCA6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596236

Catalog No. PIPA596236

Description

Positive Samples: 293T; Cellular Location: Membrane, Multi-pass membrane protein Immunogen sequence: RLKCAGSSMF LKRRWGLGYH LSLHRNEICN PEQITSFITH HIPDAKLKTE NKEKLVYTLP LERTNTFPDL FSDLDKCSDQ GVTGYDISMS TLNEVFMKLE GQSTIEQDFE QVEMIRDSES LNEMELAHSS FSEMQTAVS.

The ATP-binding cassette (ABC) superfamily is comprised of transmembrane proteins involved in energy-dependent transport of a variety of substrates across membranes. ABCA6 is a 1,617 amino acid protein belonging to the ABC transporter family. ABCA6 is up-regulated during monocyte differentiation into macrophages, suggesting a role in macrophage lipid homeostasis. ABCA6 contains two ABC transporter domains and is expressed as three isoforms produced by alternative splicing. ABCA6 is present at highest levels in adult liver, with significant levels found in many adult tissues and fetal lung, kidney and liver.

Specifications

• Antigen: ABCA6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCA6
• Gene Alias: 6330565N06Rik; ABC transporter ABCA6; Abca6; ATP binding cassette subfamily A member 6; ATP-binding cassette A6; ATP-binding cassette sub-family A member 6; ATP-binding cassette transporter sub-family A member 6; ATP-binding cassette, subfamily A (ABC1), member 6; ATP-binding cassette, sub-family A (ABC1), member 6; EST155051
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23460, 303639, 76184
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.51 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q8K441, Q8N139
• Gene Symbols: ABCA6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 690-828 of human ABCA6 (NP_5250232).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov