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Invitrogen™ ABCA7 Polyclonal Antibody
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Catalog No. PIPA534396
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100 μg
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Catalog No. Quantity
PIPA534396 100 μg
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Catalog No. PIPA534396 Supplier Invitrogen™ Supplier No. PA534396
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Description

Rabbit Polyclonal Antibody

A suggested positive control is 293 cell lysate. PA5-34396 can be used with blocking peptide PEP-1438.

ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCA7
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Abca7
Gene Accession No. Q8IZY2
Gene Alias ABC 1 antibody; ABC Transporter 1; ABC1; ABC1 antibody; Abc51; Abca7; ABCA-SSN; ABCX; AD9; ATP binding cassette subfamily A member 7; ATP-binding cassette sub-family A member 7; ATP-binding cassette sub-family A member 7; LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 7; ATP-binding cassette, subfamily A (ABC1), member 7; ATP-binding cassette, sub-family A (ABC1), member 7; ATP-binding cassette, sub-family A, member 7; autoantigen SS-N; CERP; CERP antibody; EC 2.2.1.1; EC 3.6.3; EC 3.6.3.41; FLJ40025; Macrophage ABC transporter; Phospholipid-transporting ATPase ABCA7; phospholipid-transporting ATPase ABCA7; ATP-binding cassette sub-family A member 7
Gene Symbols Abca7
Host Species Rabbit
Immunogen An 18 amino acid synthetic peptide near the amino terminus of human ABCA7.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10347
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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