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ABCA7 Rabbit anti-Human, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501734862 Shop All Proteintech Group Inc Products
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50-173-4862 150 μL
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Catalog No. 50-173-4862 Supplier Proteintech Group Inc Supplier No. 253391AP150UL
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Description

Rabbit Polyclonal Antibody

ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.

Specifications

Antigen ABCA7
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ABCA7
Gene Accession No. Q7TNJ2, Q8IZY2
Gene Alias ABCA SSN, ABCA7, ABCX, Autoantigen SS N, Macrophage ABC transporter
Gene Symbols ABCA7
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10347, 299609
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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