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Invitrogen™ ABCG1 Polyclonal Antibody
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Catalog No. PIPA5111022
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PIPA5111022 100 μL
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Catalog No. PIPA5111022 Supplier Invitrogen™ Supplier No. PA5111022
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Rabbit Polyclonal Antibody

Immunogen sequence: EYGDQNSRLV RAVREGMCDS DHKRDLGGDA EVNPFLWHRP SEEVKQTKRL KGLRKDSSSM EGCHSFSASC L Highest antigen sequence indentity to the following orthologs: Mouse - 75%, Rat - 75%.

ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCG1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ABCG1
Gene Accession No. P45844
Gene Alias ABC transporter 8; ABC8; ABCG1; ATP binding cassette subfamily G member 1; ATP-binding cassette 8; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; ATP-binding cassette, subfamily G (WHITE), member 1; ATP-binding cassette, sub-family G (WHITE), member 1; ATP-binding cassette, subfamily G, member 1; AW413978; homolog of Drosophila white; I79_011524; MGC34313; White; White protein homolog; white protein homolog (ATP-binding cassette transporter 8); WHITE1; WHT1
Gene Symbols ABCG1
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human ABCG1. Recombinant protein control fragment (Product #RP-95889).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9619
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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