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Invitrogen™ ABCG1 Polyclonal Antibody
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Catalog No. PIPA595071
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100 μg
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PIPA595071 100 μg
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Catalog No. PIPA595071 Supplier Invitrogen™ Supplier No. PA595071
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: U87 whole cell, SMMC whole cell, HELA whole cell, COLO320 whole cell, MCF-7 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCG1
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene ABCG1
Gene Accession No. P45844, Q64343
Gene Alias ABC transporter 8; ABC8; ABCG1; ATP binding cassette subfamily G member 1; ATP-binding cassette 8; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; ATP-binding cassette, subfamily G (WHITE), member 1; ATP-binding cassette, sub-family G (WHITE), member 1; ATP-binding cassette, subfamily G, member 1; AW413978; homolog of Drosophila white; I79_011524; MGC34313; White; White protein homolog; white protein homolog (ATP-binding cassette transporter 8); WHITE1; WHT1
Gene Symbols ABCG1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human ABCG1 (627-647aa ETCHFQKSEAILRELDVENAK).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11307, 85264, 9619
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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