Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC CP-945598 HCl 686347-12-6 25mg
Supplier: Apexbio Technology LLC A143525
CP-945598 HCl (CAS 686347-12-6) is a highly selective and potent antagonist of the cannabinoid receptor type 1 (CB1) a G protein-coupled receptor predominantly expressed in the central and peripheral nervous systems and implicated in the regulation of energy homeostasis The compound exhibits strong affinity for CB1 with Ki values of 0 7 nM (binding) and 0 12 nM (functional assay) In preclinical studies CP-945598 HCl antagonized CB1 agonist-induced CNS effects in mice such as hypothermia antinociception reduced locomotion and catalepsy and dose-dependently reduced food intake and increased energy expenditure in rats and obese mouse models These properties support its utility in investigating CB1-mediated signaling and metabolic regulation
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction