CPC Scientific Ac-Asp-Thr-Glu-Asp- Val-Val-Pro-Nva-O-4-phenylazophenyl ester 1MG

Supplier:  CPC Scientific SUBS050B

This peptide is a spectrophotometric substrate for a chymotrypsin-like serine protease encoded by a hepatitis C virus (HCV) and is promising target antiviral therapeutic development. Due to the low catalytic efficiency of HCV?s serine protease, this continuous spectrophotometric substrate is a ideal for both kinetic analysis and high-throughput screening. It is hydrolyzed by HCV protease under second-order rate kinetics with a constant (kcat/Km) of 80,000 ? 10,000 M^-1s^-1.SEQUENCE: Ac-Asp-Thr-Glu-Asp- Val-Val-Pro-Nva-O-4-phenylazophenyl esterONE-LETTER SEQUENCE: Ac-DTEDVVP-Nva-O-4-phenylazophenyl esterMOLECULAR FORMULA: C51H70N10O17MOLECULAR WEIGHT: 1095.2STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: SYNONYMS: RESEARCH AREA: Protein Kinases and Phosphatases REFERENCES:Zhang R, Beyer BM, Durkin J et al Anal Biochem 270:268-275 (1999)SKU(s): SUBS-050A, SUBS-050B

Catalog No. 50-211-0529