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Tocris Bioscience™ Ac-FLTD-CMK
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Catalog No. 72421
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72-421 1 mg
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Catalog No. 72-421 Supplier Tocris Bioscience™ Supplier No. 7242/1
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Description

Potent and selective inhibitor of caspases 1, 5 and 4

Ac-FLTD-CMK is a potent and selective inhibitor of caspases 1, 5 and 4 (IC50 values = 46.7 nM, 0.33 μM, 1.49 μM, respectively), and inhibits murine caspase-11 at 10 μM. Ac-FLTD-CMK inhibits cleavage of gasdermin D by caspases, suppresses pyroptosis and reduces IL-1β release in macrophages.

Specifications

Purity 95%
CAS 2376255-48-8
Content And Storage Store at -20°C
Quantity 1 mg
Target Entry Caspase Inhibitors
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