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Invitrogen™ ACE Monoclonal Antibody (3.1.1)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA110822
Description
MA1-10822 detects Angiotensin Converting Enzyme from human, bovine, and mouse samples. MA1-10822 has been successfully used in ELISA, immunohistochemistry, and flow cytometry applications. The MA1-10822 immunogen is Angiotensin converting enzyme purifie.
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes-the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
Specifications
ACE | |
Monoclonal | |
0.7 mg/mL | |
PBS with no preservative; pH 7.4 | |
P09470, P12820, P12821, P47820 | |
Ace | |
Angiotensin converting enzyme purified from rat lung. | |
100 μg | |
Primary | |
Human, Mouse, Rat, Bovine | |
Antibody | |
IgM |
ELISA, Flow Cytometry, Immunohistochemistry | |
3.1.1 | |
Unconjugated | |
Ace | |
ACE; ACE1; ACE-T; angiotensin 1 converting enzyme 1; angiotensin converting enzyme; angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme 1; angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript; angiotensin I-converting enzyme (Dipeptidyl carboxypeptidase 1); angiotensin-converting enzyme; Angiotensin-converting enzyme, soluble form; angiotensin-converting enzyme; LOW QUALITY PROTEIN: angiotensin-converting enzyme; angiotensin-converting enzyme-like; AW208573; carboxycathepsin; CD143; CD143 antigen; DCP; Dcp1; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase 1 (Angiotensin I-converting enzyme); dipeptidyl carboxypeptidase I; dipeptidyl peptidase; I79_009670; ICH; kininase II; LOC103158533; MGC26566; MVCD3; peptidase P; peptidyl dipeptidase i; StsRR92; testicular ECA | |
Mouse | |
Purified | |
RUO | |
11421, 1636, 24310, 509484 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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