Invitrogen™ ACE Monoclonal Antibody (3.1.1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA110822

Catalog No. 01671850

Description

MA1-10822 detects Angiotensin Converting Enzyme from human, bovine, and mouse samples. MA1-10822 has been successfully used in ELISA, immunohistochemistry, and flow cytometry applications. The MA1-10822 immunogen is Angiotensin converting enzyme purifie.

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes-the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

Specifications

• Antigen: ACE
• Classification: Monoclonal
• Concentration: 0.7 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P09470, P12820, P12821, P47820
• Gene Symbols: Ace
• Immunogen: Angiotensin converting enzyme purified from rat lung.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine
• Product Type: Antibody
• Isotype: IgM

• Applications: ELISA, Flow Cytometry, Immunohistochemistry
• Clone: 3.1.1
• Conjugate: Unconjugated
• Gene: Ace
• Gene Alias: ACE; ACE1; ACE-T; angiotensin 1 converting enzyme 1; angiotensin converting enzyme; angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme 1; angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript; angiotensin I-converting enzyme (Dipeptidyl carboxypeptidase 1); angiotensin-converting enzyme; Angiotensin-converting enzyme, soluble form; angiotensin-converting enzyme; LOW QUALITY PROTEIN: angiotensin-converting enzyme; angiotensin-converting enzyme-like; AW208573; carboxycathepsin; CD143; CD143 antigen; DCP; Dcp1; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase 1 (Angiotensin I-converting enzyme); dipeptidyl carboxypeptidase I; dipeptidyl peptidase; I79_009670; ICH; kininase II; LOC103158533; MGC26566; MVCD3; peptidase P; peptidyl dipeptidase i; StsRR92; testicular ECA
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 11421, 1636, 24310, 509484
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

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