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AdipoGen ACE2 human ELISA Kit

Supplier: AdipoGen AG45B0023KI01

Colorimetric Sandwich ELISA Assay. Sample Type Cell Culture Supernatant,Plasma,Serum,Urine. Range 0.0625 to 4ng/ml. Sensitivity 40pg/ml. Human ACE2 gene, localized in X chromosome, encodes for a 805 amino acid protein with an N-terminal signal sequence, a metalloprotease zinc binding site HEMGH and a hydrophobic region near the C-terminus acting as a membrane anchor transmembrane domain. Angiotensin-converting enzyme 2 ACE2 is a type I transmembrane metallocarboxypeptidase within the renin-angiotensin system RAS, which plays a key role in blood pressure regulation, fluid and electrolyte balance, thirst, cardiac/renal function and growth. ACE2 is expressed on the cell surface of type 2 alveolar epithelial cells in the lungs as well as on cells in many other tissues. ACE2 shares approximately 60% homology with ACE, the other key enzyme of the RAS system.
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