Invitrogen™ H4ac pan-acetyl (K5,K8,K12,K16) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA184526

Catalog No. PA184526

Description

Rabbit anti Histone H4 (Acetylated) antibody was raised against the tetra-acetylated form of histone H4 and recognizes acetylated isoforms of histone H4.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: H4ac pan-acetyl (K5,K8,K12,K16)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H4C1
• Gene Alias: acetyl Histone H4; Acetyl-H4 K5 K8 K12 K16; Acetyl-H4 Lys5 Lys8 Lys12 Lys16; Acetyl-Histone H4 K5 K8 K12 K16; Acetyl-Histone H4 Lys5 Lys8 Lys12 Lys16; FO108; H4; H4 ac pan-acetyl; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4ac; H4c1; H4c11; H4C12; H4C13; H4c14; H4C15; H4c2; H4c3; H4c4; H4C5; H4c6; H4C8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K12; H4K12a; H4K12ac; H4K16; H4K16ac; H4K5; H4K5,8,12,16ac; H4K5ac; H4K8; H4K8ac; H4Lys5,8,12,16ac; H4M; HIST1H4; HIST1H4A; Hist1h4b; HIST1H4C; Hist1h4d; HIST1H4E; Hist1h4f; Hist1h4h; Hist1h4i; HIST1H4J; Hist1h4k; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; histone H4; Histone H4 acetyl; Histone H4A; Histone H4K12; Histone H4K16; Histone H4K5; Histone H4K8; histone IV, family 2; X04652
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, All species
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: Whole serum with <0.1% sodium azide
• Gene Accession No.: P62805, P62806
• Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
• Immunogen: KLH-conjugated peptide acetylated at lysines 5,8,12,16: NSGRGAcKGGAcKGLGAcKGGAAcKRHYCC.
• Regulatory Status: RUO
• Gene ID (Entrez): 121504, 319158, 326619, 326620, 8294, 8359, 8363, 8366, 8367, 8370, 97122
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid