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Invitrogen™ Acid Phosphatase 1 Polyclonal Antibody
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Catalog No. 01675108
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100 μg
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Catalog No. Quantity
01-675-108 100 μg
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Catalog No. 01-675-108 Supplier Invitrogen™ Supplier No. PA141703
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Description

Rabbit Polyclonal Antibody

PA1-41703 detects Acid phosphatase 1, isoform b. Suggested positive control: antigen standard for ACP1 (transient overexpression lysate), human liver protein, liver lysate. Sequence identity: 86% with canine and 80% with rat proteins.

Low molecular weight protein tyrosine phosphtases, including the human red cell phosphatase, HCPTP, are widely expressed cytosolic proteins of approximately 18 kDa that exist in distinct isoforms and are highly selective for phosphotyrosine over phosphoserine or phosphotyrosine. The HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta are fast and slow forms of red cell acid phosphatase5. Like other tyrosine phosphatases, HCPTP is sensitive to inhibition by vanadate, and has a catalytic mechanism that involves formation of a cystinylphosphate intermediate6. The crystal structure of the bovine heart derived enzyme BHPTP shows a four-stranded central parallel b sheet with flanking a helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Acid Phosphatase 1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.05% sodium azide
Gene ACP1
Gene Accession No. P11064, P24666, P81693
Gene Alias 4632432E04Rik; acid phosphatase; acid phosphatase 1; acid phosphatase 1, soluble; acid phosphatase of erythrocyte; acp1; Acp-1; Acp1-PA; adipocyte acid phosphatase; Adult cuticle protein 1; AI427468; CG7216; CG7216-PA; cytoplasmic phosphotyrosyl protein phosphatase; Dacp-1; Dmel\CG7216; Dmel_CG7216; HAAP; HAAP betaÊ; hypothetical protein; LMW-PTP; LMW-PTPase; LMW-PTP-I low molecular weight phosphotyrosine protein phosphatase isozyme 1; Low molecular weight cytosolic acid phosphatase; low molecular weight phosphotyrosine protein phosphatase; MGC111030; MGC3499; phosphatase 1, soluble; protein tyrosine phosphatase; ptpase; RCJMB04_11a4; Red cell acid phosphatase 1; RH03221p; testicular secretory protein Li 37; Unknown (protein for MGC:128334)
Gene Symbols ACP1
Host Species Rabbit
Immunogen A portion of amino acids 40-80 of human ACP1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100737301, 280977, 52
Target Species Human, Bovine, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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