Invitrogen™ Acid Phosphatase 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141703

Catalog No. 01-675-108

Description

PA1-41703 detects Acid phosphatase 1, isoform b. Suggested positive control: antigen standard for ACP1 (transient overexpression lysate), human liver protein, liver lysate.

Low molecular weight protein tyrosine phosphtases, including the human red cell phosphatase, HCPTP, are widely expressed cytosolic proteins of approximately 18 kDa that exist in distinct isoforms and are highly selective for phosphotyrosine over phosphoserine or phosphotyrosine. The HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta are fast and slow forms of red cell acid phosphatase5. Like other tyrosine phosphatases, HCPTP is sensitive to inhibition by vanadate, and has a catalytic mechanism that involves formation of a cystinylphosphate intermediate6. The crystal structure of the bovine heart derived enzyme BHPTP shows a four-stranded central parallel b sheet with flanking a helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.

Specifications

• Antigen: Acid Phosphatase 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACP1
• Gene Alias: 4632432E04Rik; acid phosphatase; acid phosphatase 1; acid phosphatase 1, soluble; acid phosphatase of erythrocyte; acp1; Acp-1; Acp1-PA; adipocyte acid phosphatase; Adult cuticle protein 1; AI427468; CG7216; CG7216-PA; cytoplasmic phosphotyrosyl protein phosphatase; Dacp-1; Dmel\CG7216; Dmel_CG7216; HAAP; HAAP betaÊ; hypothetical protein; LMW-PTP; LMW-PTPase; LMW-PTP-I low molecular weight phosphotyrosine protein phosphatase isozyme 1; Low molecular weight cytosolic acid phosphatase; low molecular weight phosphotyrosine protein phosphatase; MGC111030; MGC3499; phosphatase 1, soluble; protein tyrosine phosphatase; ptpase; RCJMB04_11a4; Red cell acid phosphatase 1; RH03221p; testicular secretory protein Li 37; Unknown (protein for MGC:128334)
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100737301, 280977, 52
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.2% gelatin and 0.05% sodium azide
• Gene Accession No.: P11064, P24666, P81693
• Gene Symbols: ACP1
• Immunogen: Synthetic peptide corresponding to residues 40-80 of humanACP1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Bovine, Pig
• Product Type: Antibody
• Isotype: IgG